Everybody may have never thought about this-protein causing prostate cancer.
An article published on The Daily Mail UK revealed that GPR 158, a protein based molecule, produces tendencies of increasing risks of ineffective hormonal therapies against prostate cancer. Hence, scientists concluded that individuals that take in high amounts of protein foods have higher risks of getting prostate cancer.
American scientist, Nitin Patel, an expert at the University of Southern California, revealed the process of prostate cancer development in connection to high protein intake. He said, "When a prostate cancer tumour is in its early stages, it depends on hormones called androgens to grow."
"Eventually it progresses to a more lethal form, called castration-resistant prostate cancer (CRPC), and is resistant to drugs that block androgen receptors. We found that GPR158, unlike other members of the GPCR family, is stimulated by androgens, which in turn stimulates androgen receptor expression, leading to tumour growth."
Accredited medical researchers used a Pten knockout mouse prostate cancer model in their search for answers for protein intake and cancer association, as revealed in an article in University of Southern California News Team. The USC team of researchers worked in close cooperation with researchers, Mitchell Gross, Chun-Peng Liao and Pradip Roy-Burman of the Keck Medicine School in the university.
This team is now hard at work in studying the association between GPR158 and CRPC in the development of diseases. The researchers are also penetrating through the studies of effective GPR158 hormonal therapeutic methods.
The studies yielded by these experts paves the way for more effective serious diseases treatments, hence, prolonging longevity.