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Obesity helps patients with kidney cancer survive

| Sep 15, 2016 11:44 AM EDT

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Obesity could prolong the life of kidney cancer patients. This is the result of studies conducted by researchers and scientists.

There are great risks of having cancer particularly kidney cancers if people have high body mass index according to research. The American Cancer Society said that with the probability of 9 out of 10, the proliferation of the most common kinds of cancer is triggered by hormonal changes caused by obesity.

Poorer chances of cancer healing would occur if a patient has obesity. But in the case of renal cell carcinoma (RCC) or kidney cancer, the recent studies shows that it is not really what happens

Kidney cancer patients who have obesity are found to have decrease of progression of kidney cancer, better chances of survival or greater probability of being treated compared to kidney cancer patients who have normal weight. This was concluded in the research done with 2,100 kidney cancer patients in the year 2013, Medical News Today reported

The kidney cancer treatment could aim for the FASN or fatty acid synthase. In the process called lipogenesis or fatty acids production, the fatty acid synthase (FASN) does the most important role. In many kinds of cancer, it has been discovered that this gene has been overexpressing. Thus, patients with cancer that includes the kidney cancer patients get bad or poor outcomes.

As the result of the research, the scientists are speculating that compared to kidney cancer patients who have normal weight or are underweight, kidney cancer patients suffering from obesity survive and live for a longer time because they have reduced expression of fatty acid synthase (FASN), as reported by Science Daily.

It is still not yet known why in kidney cancer patients who have obesity FASN is downregulated. Downregulation is the process wherein there is a reduction of cellular components or parts.

However, scientists say that the findings show a reason for tests and experiments to target at inhibiting or preventing the FASN expression in kidney cancer patients regardless of the patients' weight-- just in order to treat them and to come out with better outcomes.

The researcher, Toni K. Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana-Farber noted that as a potential treatment for kidney cancer, they are looking into testing the FASN inhibitor in animal models.

Meanwhile, here's a video on how to do a kidney cleanse:

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