Reddam Racing's Nyquist, the 1-2 favorite, breezed past a field of six in topping the Del Mar Futurity with a winning margin of 3-3/4 lengths on Monday.
Nyquist and jockey Mario Gutierrez covered the seven furlongs in 1:23.28, ESPN reported.
Swipe came in second with Blameitonthelaw at third.
Nyquist is now 3-0 in its brief career, which includes winning of the Best Pal Stakes by 5 1/4 lengths on Aug. 8 at Del Mar.
Trainer Doug O'Neill described Nyquist as a super horse, which like any great athlete needs to stay healthy to "do some do some big things."
Kent Desormeaux, who was aboard Swipe, admitted that Nyquist was just too good, according to USA Today.
Bred in Kentucky by Summerhill Farm, Nyquist is a son of Uncle Mo, who went undefeated as a 2-year-old and was the early Kentucky Derby favorite in 2011 before being scratched the day before the race due to a gastrointestinal infection.
Nyquist is also the first foal out of the Forestry mare Seeking Gabrielle. She has a yearling filly by Blame and was bred to Flatter for 2016.
The win capped a spectacular day for owner J. Paul Reddam and trainer Doug O'Neill who combined to win the Hopeful Stakes at Saratoga Race Course with Ralis.
O'Neill becomes the first trainer to win both races in the same year.
It was O'Neill's second Futurity win and sending out Stevie Wonderboy to victory in 2005.
Archaeo, also trained by O'Neill, finished last in the six-horse field.
With Nyquist and Ralis in his stable, owner Paul Reddam can't is thinking ahead to next year's Kentucky Derby.
The victory brought in $180,000 and increased Nyquist's career earnings to $333,600.
Nyquist was purchased for $400,000 in March.