Erstwhile league leader Manchester United (5-2-1, 16 points) will look to retain the 2015-2016 Premier League's top spot as it clashes with hard-fighting Everton (3-1-4, 13 points) at the Goodison Park on October 17, Saturday.
The Red Devils are coming off a 0-3 humiliation in the hands of Arsenal at the Emirates Stadium on October 4, as reported by ESPN.
Gunners' winger Alexis Sánchez scored a double at the 6th and 19th minutes while midfielder Mesut Özil had another one at the 7th to complete the romp for Arsene Wenger's team.
Louis van Gaal's boys were not able to respond from Arsenal's quick opening attack as they struggled to find the back of David Ospina's net the whole game. The 63-year-old Dutch mentor blamed his squad's lack of energy and intensity for the lopsided result.
Meanwhile, Everton settled for a 1-1 draw versus Liverpool for a Merseyside derby at the Goodison Park last October 4, which was Brendan Rodgers last game as the Reds' manager, via Fox Sports.
Liverpool's Danny Ings opened the scoring four minutes before the halftime break, but Toffees striker Romelu Lukaku, who recently expressed his desire to play alongside Wayne Rooney at United, equalized the count right before the interlude.
Van Gaal would be eager to bounce back from just their second loss of the season in this match against Roberto Martínez's wards and he needs Rooney and Memphis Depay to elevate their games alongside the magnificent Anthony Martial to have a chance.
The predicted result is a tough 2-1 decision for Manchester United.
Everton starting lineup (4-2-3-1 formation): Howard; Galloway, Funes Mori, Browning, Jagielka; Naismith, McCarthy; Barkley, Deulofeu, Barry; Lukaku
Manchester United starting lineup (4-2-3-1 formation): De Gea; Darmian, Smalling, Blind, Young; Mata, Depay; Carrick, Rooney, Schweinsteiger; Martial