Erstwhile frontrunner Inter Milan (5-1-1, 16 points) will take on the challenge of the struggling defending champions Juventus (2-3-2, 8 points) in a high-profile Serie A 2015-2016 matchup at the Stadio Giuseppe Meazza on Sunday, October 18.
Internazionale had been winless in their last two games, making them give up the league leadership to Fiorentina in the process.
Roberto Mancini's squad is coming off a disappointing 1-1 draw with middling team Sampdoria at the Stadio Luigi Ferraris on October 4, via Soccerway.
I Blucerchiati's Colombian striker Luis Muriel managed to left-foot a goal from close range at the 51st minute to give the hosts a 1-0 lead. Inter's Croatian winger Ivan Perisic tied the count at the 76th to save the point for his team and avoid further demotion in the league table.
Meanwhile, Juve found a ray of hope in their last game via a 3-1 thrashing of cellar-dwelling Bologna at the Juventus Stadium also last October 4, as per SkySports.
Álvaro Morata, Paulo Dybala, Sami Khedira had a goal each for La Vecchia Signora at the 33rd, 52nd, and 63rd minute marks respectively after I Felsinei's midfielder Anthony Mounier opened the scoring at the 5th.
Massimiliano Allegri hopes this would be the start of a winning run for Juve, but facing the former league leaders would be a tough challenge for his squad.
Prediction: Inter Milan drops Juventus, 3-1.
Inter Milan starting lineup (4-3-2-1 formation): Handanovic; Santon, Medel, Murillo, Alex; Guarin, Melo, Kondogbia; Palacio, Perisic; Icardi
Juventus starting lineup (4-3-3 formation): Buffon; Barzagli, Bonucci, Chiellini, Evra; Khedira, Hernanes, Pogba; Cuadrado, Dybala, Morata