The surprise hit of 2016 was Fox's "Deadpool" movie. It was even more successful than their own X-Men movie, "X-Men: Apocalypse."
Perhaps the easy suggestion for the studio (and probably what the fans want) is a crossover between Deadpool and the X-Men. That could make the franchise relevant again.
However, there is a definite question on whether they are actually in the same universe. "Deadpool" was so irreverent that it was not exactly very clear. Not to mention that many reboots that Fox has done with their Universe building effort. It's not as cut-and-dry as the Marvel Cinematic Universe, for instance.
So, is Deadpool really part of the X-Men universe and consequently, will a crossover finally happen? This was addressed by writer Paul Wernick in an interview with The Hollywood Reporter.
"What's nice is Deadpool exists in his own universe. He's part of the larger X-Men universe, but in a way he isn't. He interacts with that world but he is in the present. We don't deal with the '60s or the '70s or the future. It's here and now. More than anything, I think he's going to have his fun with what they do in the other franchise. But fortunately, we don't have to play by those same rules. Deadpool is a movie that did break all the rules. And I think we're going to continue to break those rules. That involves knowing that he's in a movie, talking to the audience, breaking that fourth wall, a characteristic that they established so brilliantly in the comics way back when. So yeah, I do think that timelines are something that we can make fun of and don't have to be slave to."
The rules are meant to be broken when you're dealing with Deadpool and that's part of the character's allure-you don't know what to expect. That is probably the edge they have over other universes.
But the question still stands: will the X-Men ever appear in a Deadpool sequel? That was then addressed by writer Rhett Reese on Collider (h/t Cinema Blend).
"You kinda don't want a Ferrari in Deadpool unless it's for a real purpose in the sense that Deadpool is a gritty, grimy, smaller thing, with characters you aren't as familiar with. It's a little bit like lovable losers. It's not the A-list of superheroes, necessarily. ... The occasional cameo or appearance by an A-list type person could be really funny and/or dramatic. So we have an eye open for those things, but we don't want to just put people in it because we can now, if that makes sense."
Not a definite yes or no, but they won't do it just for the sake of inserting the characters there. It's possible but Deadpool is definitely their own franchise and they have definitely earned their right to stand alone, even though they failed to net an Oscar nomination.
Yes, comic book fans have been hoping for an Oscar nomination. There were some who proposed that for Marvel Studios "Captain America: The Winter Soldier," probably one of the most serious superhero movies ever made. "Deadpool" was the polar opposite, but the Academy still wasn't interested.