"Fairy Tail 466" will feature Natsu will fail to kill Zeref; a failure which will eventually be the death of him.
"Fairy Tail's" previous chapter had major revelations including Zeref being Natsu's brother, plus Natsu turned out to be Etherious Natsu Dragneel.
Zeref lays out the card in the table revealing that he wants Natsu to kill him. This is the reason why he sent his brother Eclipse in the first place. Unfortunately, 400 years had passed and Zeref basically changed his mind.
The Japanese manga series' chapter 465, Zeref is shown saying the lines to his brother, "You can't stop me anymore. Goodbye Natsu."The following chapter is called "Assassin," and after the huge reveal, big questions still remain, iSchool Guide reported.
Many Manga Helpers are convinced that while Natsu will not hesitate to reveal information about the dragon slayers, he might deny that he is Etherious Natsu Dragneel.
Happy will not tell either, especially since he knows that a revelation like that will only bring chaos to the Guild, MCM reported.
Reports also said that Gray is out to take out Natsu's head. Many fans are speculating that if they meet, it will not be the best moment for both of them to settle internal conflicts.
"Fairy Tail 466" will also feature the link between Layla and Brandish, which will bring another huge mystery to the story that is still unresolved to this day. Layla has played a huge part in bringing the dragon slayers beyond the times.