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point mutation
Deaminase is attached by a linker to nuclease-deficient CRISPR/Cas9. Guide RNA recognizes the DNA sequence of target genome and the deaminase modifies the base of the unwound DNA.
Researchers Develop New Genome Editing Technique that Doesn’t Splice DNA

ByArhur Dominic Villasanta | Aug 28, 2016 04:57 AM EDT

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