• Indianapolis Colts quarterback Andrew Luck (#12) against the New England Patriots.

Indianapolis Colts quarterback Andrew Luck (#12) against the New England Patriots. (Photo : Getty Images)

The New Orleans Saints (2-4) are coming off an impressive home victory in Week 6 and they hope to sustain the momentum on the road as they visit the Indianapolis Colts (3-3) at the Lucas Oil Stadium on Sunday for a 2015 NFL season encounter.

Quarterback Drew Brees and tight end Ben Watson led the Saints to a 31-21 conquest of the previously undefeated Atlanta Falcons at the Mercedes-Benz Superdome on October 15, handing head coach Dan Quinn and his boys their first loss of the season, via CBS Sports.

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Meanwhile, the Colts played superbly against their arch-rivals, the New England Patriots, in the highly-anticipated "Deflategate rematch", but a curious trick play gone wrong late in the third quarter basically handed out the 34-27 decision to their opponents, as per Bleacher Report.

Quarterback Andrew Luck returned in the game for the Colts and had a big game while wide receiver T.Y. Hilton also had a great night with six catches for 74 yards and a touchdown.

Head coach Chuck Pagano will look to bury the past and try to bounce back against the Saints in this one with Luck back in harness. The team will also take advantage of New Orleans' weak rushing defense by unleashing running back Frank Gore.

Prediction: Colts win, 28-21.

New Orleans Saints starting lineup

Offense: Brees (QB), Ingram (RB), Johnson (FB), Cooks (WR1), Coleman (WR2), Watson (TE), Peat (LT), Lelito (LG), Unger (C), Kelemete (RG), Strief (RT)

Defense: Richardson (DE), Jenkins (DT), Williams (DT), Jordan (DE), Kikaha (OLB), Anthony (MLB), Ellerbe (OLB), Breaux (CB1), Browner (CB2), Vaccaro (SS), Byrd (FS)

Indianapolis Colts starting lineup

Offense: Luck (QB), Gore (RB), Doyle (FB), Hilton (WR1), Johnson (WR2), Allen (TE), Castonzo (LT), Mewhort (LG), Holmes (C), Thornton (RG), Reitz (RT)

Defense: Langford (DE), Parry (NT), Anderson (DT), Cole (OLB), Jackson (ILB), McNary (ILB), Walden (OLB), Toler (CB1), Davis (CB2), Adams (SS), Lowery (FS)