Fiorentina (3-1-0, 9 points) and Bologna (1-3-0, 3 points) are in opposite ends of the 2015-2016 Serie A league table and they are scheduled to face one another on Wednesday, September 23 at the Stadio Artemio Franchi in Florence.
Viola settled on a 1-0 road victory over last season's Serie B champs Carpi at the Stadio Alberto Braglia in Modena on Sunday.
Senegalese striker Khouma Babacar continues his outstanding performance so far in the season with two goals in two appearances for Paulo Sousa's squad.
Babacar found the net at the 35th-minute versus I Biancorossi after a right-foot rebound on his own left-foot shot that hit the post, which came from a magnificent cross from team captain Manuel Pasqual. I Gigliati never relinquished the lead from there until full time, via SB Nation.
Meanwhile, newly-promoted club Bologna beat cellar-dweller and fellow newcomer Frosinone, 1-0, to snatch their first win of the season after starting with three consecutive defeats, as per Goalsaim.
I Felsinei opened the season with close losses to Lazio, Sassuolo, and Sampdoria. Facing possible relegation again, Delio Rossi's squad relied on French midfielder Anthony Mounier to deliver the goal.
It came early in the first half as the 27-year-old winger left-footed a shot from a difficult angle towards the bottom right corner after receiving a pass from Greek defender Marios Oikonomou.
Rossi hopes to carry over the momentum against Viola, but I Rossoblu is no match for Fiorentina's overall depth and experience.
Prediction: A 2-0 decision for Fiorentina.
Fiorentina starting lineup (4-3-3 formation): Tatarusanu; Tomovic, Astori, Alonso, Pasqual; Valero, Verdú, Vecino; Bernarderschi, Babacar, Rossi
Bologna starting lineup (4-2-3-1 formation): Mirante; Ferrari, Rossettini, Maietta, Masina; Turan, Zapata; Mounier, Brienza, Giaccherini; Destro