• The Flash and Supergirl will crossover in an episode of "Supergirl" on March 2016.

The Flash and Supergirl will crossover in an episode of "Supergirl" on March 2016. (Photo : Facebook/The Flash)

New details for "Supergirl" TV series will feature synopsis for episode 16 and two villains taking on The Flash and Supergirl in the crossover episode.

The plot synopsis for "Supergirl" episode 16 titled "Falling" will feature Kara Danvers/Supergirl (Melissa Benoist) dealing with the side effects from her exposure to the red kryptonite, shifting her usual good personality into a cold, malicious and dangerous individual.

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Several images from the "Supergirl" episode also sees Kara wearing a different costume, a black Kryptonian outfit similar to her aunt Astra In-Ze (Laura Benanti), her uncle Nun (Chris Vance) and the other Phantom Zone escapees in Fort Ross, ComicBook reported.

The next episode of "Supergirl" titled "Solitude" will see Supergirl taking on another Superman villain Indigo (Laura Vandervoot) and travels to her cousin's Fortress of Solitude in order to combat her. Indigo in the TV series will also have a mysterious connection with Kara, which is yet to be revealed.

"Solitude" will air next week, while "Falling" will shown on March 14.

In other news, the "Supergirl" and "The Flash" crossover episode will feature two DC villains from the show taking on the Girl of Steel and Barry Allen/The Flash (Grant Gustin).

The title for the crossover is called "Worlds Finest" as several behind-the-scenes images were scattered throughout Twitter showing that Siobhan Smythe/Silver Banshee (Italia Ricci) will team-up with Leslie Williams/ Livewire (Britt Morgan) to take on Supergirl and The Flash, Screenrant reported.

There is also an image of Cat Grant (Calista Flockhart) in the fight as Silver Banshee and Livewire captured her as extra leverage against the heroes, seeing as both villains used to work for CatCo.

It is unknown yet how The Flash will be visiting National City as a previous episode "Welcome to Earth 2" featured a glimpse of Supergirl indicating that she's from another earth. It was rumored several weeks ago that the crossover episode could be a "musical" themed one since both Benoist and Gustin are part of hthe hit musical TV series "Glee".

The crossover could also indicate that "Supergirl" will have potential collaborations with other DC based TV series such as "Arrow", "Legends of Tomorrow", "iZombie" and many more.

"Supergirl" airs on Monday 8pm on CBS.